What is Ai|Life Smart Medical Report?

The Ai|Life SMART MEDICAL REPORT is a revolutionary innovation capable of estimating the risk of 14 disease groups from a single blood test result using artificial intelligence. Beyond the data found in a traditional blood test report, the SMART MEDICAL REPORT provides insights into possible causes of abnormal values and potential diseases, along with estimated probabilities.How? The *artificial intelligence behind the SMART MEDICAL REPORT analyzes the risk of individual diseases by comparing patterns in your data with hundreds of millions of data points from hundreds of thousands of other patients.*The SMART MEDICAL REPORT utilizes machine learning based on large-scale health data. It aligns with the European Union's strategy outlined in COM(2018) 795, adopted in Brussels on 7 December 2018, specifically section 2.5 and its second paragraph, which identifies this as a type of artificial intelligence.This approach can uncover diseases that have not yet caused symptoms and may not be apparent from deviations in standard reference values. The SMART MEDICAL REPORT can guide healthcare providers by highlighting conditions that might otherwise only be diagnosed years later or remain undetected. Through regular screenings, these conditions can potentially be identified at an early stage, providing patients with better prospects for effective treatment and recovery.

The SMART MEDICAL REPORT is capable of estimating the risk of the following 14 disease groups. Currently, the diagnostic risk assessment of the SMART MEDICAL REPORT is primarily optimized for chronic and often difficult-to-diagnose disease groups and conditions. However, it is also capable of estimating the presence of acute, rapidly progressing conditions (e.g., acute liver diseases).The SMART MEDICAL REPORT assesses the risk of cancer only when analyzing the cancer disease group, which is available in the SMART MEDICAL REPORT "Premium" risk assessment package. This feature is not included in other packages. The premium package can be ordered at this link: https://synlab.hu/okoslelet-premium-kockazatbecslo-csomag/

SMART MEDICAL REPORT is available at SYNLAB Hungary blood collection locations in the following package options:

Our latest package, the Ai|Life SMR THYROID BASIC, has been specifically developed to detect and analyze the risk of thyroid disorders.Thyroid diseases are becoming increasingly common in Hungary, often developing gradually and initially causing only mild symptoms.This makes the THYROID Ai|Life SMR an excellent choice, as it can potentially identify various thyroid conditions even before symptoms appear:

SMART MEDICAL REPORT is available at SYNLAB Hungary blood collection locations in the following package options:

We recommend that in the days following your blood draw, you check the spam folder of your email account, as the email containing the SMART MEDICAL REPORT may be classified there due to the unknown sender. You can find further assistance regarding opening the SMART MEDICAL REPORT among the Frequently Asked Questions. If you have chosen the “Premium” risk assessment package, you are also entitled to a free specialist consultation in the event that a risk for a rare or malignant disease is detected. We will connect you with our appointed specialist, who will help you interpret your results during an online consultation and compare them with your personal medical history and symptoms, and will recommend further steps based on this. The price of the package includes the possible specialist consultation. In this case, our colleagues will contact you before sending the SMART MEDICAL REPORT. The package price also includes that every generated report is reviewed and validated by a specialist.

This section contains your personal data, the key data of the laboratory test serving as the basis for the SMART MEDICAL REPORT, as well as, for quality assurance purposes, the SMART MEDICAL REPORT identifier and the version number of the software used.

Here you will find all laboratory tests, grouped, that are used by SMART MEDICAL REPORT to estimate your disease risks. These tests are transferred from your ordered laboratory test package into SMART MEDICAL REPORT and primarily serve quality assurance purposes, as well as ensuring that all information related to your tests is available in one place. In this section, you can view your completed laboratory tests and easily notice if a test result is above (marked in red) or below (marked in blue) the reference range. From left to right, the columns mean: name of the test, test classification type, test value, test unit of measurement, lower value of the test’s reference range, upper value of the test’s reference range, and the position of the test value relative to the reference range (A - below, F - above, N - normal).

The main section of SMART MEDICAL REPORT shows, based on the evaluation of artificial intelligence, which of the 14 disease groups your laboratory results may indicate the presence of, or the potential risk of developing

The 14 Disease Groups for Which SMART MEDICAL REPORT Provides Risk Assessments

Estimated Probability

The estimated probability of the presence of a disease group. This value indicates the percentage of patients with similar laboratory results to yours – included in statistical analyses – who were found to have at least one condition from the examined disease group. The probability is calculated by mathematical models and depends on: the reliability of the models used, disease prevalence, the number of tests performed, the color category (1–5) assigned to the disease’s presence.

Presence of Disease

A color-coded scale from 1 to 5 (green → yellow → red), where increasing values indicate a higher risk of the disease group being present.

Important Note: The mathematical models exclusively base their decisions on your current laboratory results. They do not account for your medical history, physical status, other diagnostic test results, or lifestyle/environmental factors-all of which are essential for establishing an accurate diagnosis. A blood test is a critical but not exclusive component of diagnosis. Never forget this. Therefore, always consult your treating physician or specialist to determine how relevant the SMART MEDICAL REPORT results are for your specific case.

1 and 2 (green–yellow-green):These basically indicate a negative result. If your estimated disease risk falls into these categories, the probability of the presence of the disease group is unlikely (1) or less likely (2) in your case.3 (yellow):Your result falls into the uncertain range; the presence of the disease is possible, but the mathematical models cannot estimate it more precisely or rule it out.4 and 5 (orange–red):These basically indicate a positive result. If your estimated disease risk falls into these categories, the probability of the presence of the disease group is rather likely (4) or likely (5) in your case. The exact probabilities corresponding to each category can be found in the Probability column.

Important Note: The mathematical models exclusively base their decisions on your current laboratory results. They do not account for your medical history, physical status, other diagnostic test results, or lifestyle/environmental factors-all of which are essential for establishing an accurate diagnosis. A blood test is a critical but not exclusive component of diagnosis. Never forget this. Therefore, always consult your treating physician or specialist to determine how relevant the SMART MEDICAL REPORT results are for your specific case.

VALUES DEVIATING FROM THE REFERENCE RANGE

Deviations from the reference range show you which test results differ from the values established for a healthy reference population. They indicate the direction (above or below) and magnitude of the deviation. For each deviation, you can learn which clinical conditions these deviations might suggest, based on decades of laboratory medicine literature. What other test values typically deviate in these conditions.

Frame: Red or blue, depending on whether the tested value deviates above (red) or below (blue) the reference range.

Test name: The name of the test that deviates from the reference range. Description of the test: A brief introduction to the test that deviates from the reference range (what it measures, why its value is important). Most common reasons for elevated (or decreased) values: According to clinical laboratory literature, which diseases or conditions are most commonly associated with the direction of the deviation from the reference range.

Other relevant laboratory tests considering the patient history, clinical presentation, and other test results: Shows which other tests tend to deviate in the same direction and which additional tests may help to better understand the underlying causes.

It is important to emphasize that artificial intelligence does not use clinical chemistry literature and does not make decisions based on deviations from the reference ranges. The AI’s decision is based on similarity patterns between your laboratory results and those of tens or hundreds of thousands of patients in each group. While there is often overlap between the two approaches (a result without deviations usually yields a negative outcome, and multiple deviations often correspond to a positive result in line with clinical literature), this is not surprising, since laboratory medicine literature also relies on decades of accumulated knowledge and statistics. Nevertheless, it is not uncommon for the summary based on deviations from reference ranges and the findings of artificial intelligence to differ. In all cases, only your specialist is authorized and responsible for establishing an accurate diagnosis, taking into account (or disregarding) the provided information.

Like all diagnostic tests, the information provided by SMART MEDICAL REPORT also has its limitations. In certain cases, the mathematical models may identify existing health risks in completely healthy individuals (biostatistical literature refers to this as a false positive) and categorize them as patients, while in other cases, they may consider actual patients to be healthy (this is referred to as a false negative). Often, there is a significant trade-off between these two cases: the more a test aims to identify all patients (i.e., reduce false negatives), the more likely it is that some healthy individuals will be categorized as “patients”. Based on this, determining accuracy is not a simple task, as accuracy largely depends on how we interpret the patterns calculated by the mathematical methods (at what level of similarity someone is considered “ill,” and at what level “healthy”). In biostatistics, diagnostic accuracy is therefore often expressed using the ROC-AUC (receiver operating characteristic – area under curve) curve. The value of this metric is 0.5 in the case of random categorization (the best example is “flipping a coin”) and 1.0 in the case of perfect categorization (where the model never makes a mistake). The average combined AUC value of the models used by SMART MEDICAL REPORT is 0.93. This is a high value and indicates very high average accuracy.

The accuracy of SMART MEDICAL REPORT is further demonstrated by the pilot testing conducted jointly with SYNLAB Hungary between May and September 2021. During this evaluation, internists and laboratory specialists assessed SMART MEDICAL REPORT’s findings against blood test results. Experienced specialists agreed with SMART MEDICAL REPORT’s conclusions in 95% of cases based on the analysis of 785 lab reports. These results reflect the extensive work and testing behind the SMART MEDICAL REPORT project, aimed at providing you with the most accurate results possible. However, this does not mean SMART MEDICAL REPORT is error-free. In most models (though not all), SMART MEDICAL REPORT prioritizes reducing false negatives (i.e., minimizing the risk that a disease remains undetected if the report classifies a patient as healthy). This approach unintentionally increases false positives (i.e., healthy individuals may receive a positive diagnosis). This trade-off aligns with standard diagnostic testing practices and means: You may receive a positive risk assessment for diseases you do not have. If your report indicates a positive result for any condition, consult your treating physician or GP immediately to confirm or rule out the diagnosis.

By ordering SMART MEDICAL REPORT, you acknowledge and accept the potential physical (for example, but not limited to, the physical risks of additional confirmatory examinations) and psychological (for example, but not limited to, anxiety and stress about the possibility of having a health problem) risks involved. It is important to emphasize that while SMART MEDICAL REPORT makes every effort to provide the most accurate results possible-including specialist validation of some reports before delivery-it is not an officially certified medical product and as such, can in no way replace or override the opinion and/or diagnosis of a specialist physician. The information provided in SMART MEDICAL REPORT serves solely as information for your specialist, who may consider, accept, or disregard its content at their own discretion. SMART MEDICAL REPORT is purely a computer-generated interpretation, for which (and specifically, but not exclusively, for any possible inaccuracies) neither the issuer, DiagnostIQ Kft., nor any partners involved in the SMART MEDICAL REPORT service assume any responsibility.It is also important to note that the accuracy of risk classifications increases proportionally with the number of laboratory tests included, and at least a “large routine” laboratory panel or an equivalent package is required for meaningful interpretation of SMART MEDICAL REPORT. If you use a laboratory package containing fewer tests, SMART MEDICAL REPORT is not reliable at all (for more information about the laboratory packages available with the SMART MEDICAL REPORT service, see:

Where is Ai|Life SMART MEDICAL REPORT available?